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POLYREST-INJ (Polymyxin-B Injection) is a potent, hospital-grade antibiotic used for the treatment of severe and life-threatening bacterial infections, particularly those caused by multidrug-resistant gram-negative organisms. It belongs to the polymyxin class of antibiotics and is often considered a last-line or reserve therapy when standard antibiotics fail to work. This medication is administered only under strict medical supervision due to its powerful action and the need for careful monitoring of kidney and neurological function. What is Polymyxin-B? Polymyxin-B is a cyclic polypeptide antibiotic that works by targeting the outer cell membrane of gram-negative bacteria. It binds to bacterial phospholipids, disrupts membrane integrity, and causes leakage of essential cellular components, leading to rapid bacterial death. Benefits of POLYREST-INJ ✔ Effective against multidrug-resistant bacteria ✔ Rapid bactericidal action ✔ Life-saving option in critical care settings ✔ Useful when other antibiotics fail ✔ Suitable for severe hospital-acquired infections
